INTRACRANIAL PRESSURE and ASSESSMENT SCREENING SYSTEM
A non-invasive way to triage & continuously monitor intracranial pressure (ICP) far earlier than currently possible in the care journey
IPASS
THE CRANIOSENSE SOLUTION
IPASS measures intracranial pressure in seconds.
CranioSense has developed IPASS, a technology that measures intracranial pressure in seconds, without the need to drill a hole in the skull or insert a sensor into the brain.
IPASS measures intracranial pressure (ICP) with an easy-to-use system that only requires a patch on the forehead, two clip-on sensors, and a handheld device the size of an iPad.
“Non-invasive ICP is the holy grail of neurosurgery.”
— Neurosurgeon (Florida)
Previous and Ongoing Studies
Healthy Human
COMPLETED
Technical risk reduction: Correlation between PTT and ICP demonstrated
ICU Gold Standard Comparison
COMPLETED
Technical risk reduction: Direct comparison to ICU gold standard shows high correlation
7 ICU sites across the US
Algorithm development and optimization
Ground truth: EVD & Bolt
Sen. 91%, Spec. 95% at diagnosing intracranial hypertension (training data)
Pilot Validation of Diagnostic Algorithm
ONGOING
Anticipated technical risk reduction: Initial validation of proprietary algorithm
Neuroradiology at Mass General Hospital
Algorithm validation against diagnostic gold standard
Ground truth: Lumbar puncture opening pressure
n=30 (anticipated completion August 2025)
Neurologist, Community Hospital (Tennessee)